Sometimes a person is very tuned into their soul attributes and life purpose, at times not at all. That is the widest distance. Then there is everything in between.
Another way of saying the same thing is that a person is very invested in physical reality and largely unaware of anything else, and other times, the person is fundamentally aware of their larger reality understanding the physical realm to be one facet of expression of their being.
For me what's challenging is when a person is hugely invested in physical reality and looking for solutions to their hardships. The solutions are always about knowing larger truth. A relationship may not go well, but it's okay. From soul perspective, the person is unfolding, learning, and through this hardship being prompted to discover her own truth, higher truth, know the essence of her being. Basically, things are okay. The world is not ending; you're just learning.
As we progress in our evolution, the learning does not stop, but it becomes easier. We know we're always learning and don't panic when challenges arise. They may be uncomfortable, but we know it's not the end of the world.
It's a great leap in growth when we arrive at this place. We can get comfortable with existence, and enjoy what's in front of us.